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If gastrointestinal symptoms become unbearable, your prescriber may recommend staying at your current dose longer before escalating, switching to a microdose GLP-1 protocol ($129/month), or exploring oral semaglutide as an alternative formulation

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Second, niacinamide is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism, mitochondrial function, and DNA repair

Breaking or chewing the tablet can alter the way the medication is absorbed and may reduce its effectiveness