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Retatrutide activates the GIP, GLP-1 and glucagon receptors that are involved with controlling hunger and satiety, allowing people to feel fuller after eating for longer

If bile reflux or severe nausea persists, dose reduction or temporary pause may be warranted before resuming escalation

Common side effects include: Nausea Vomiting Diarrhea Constipation Abdominal pain These side effects are usually mild and tend to decrease over time as your body adjusts to the medication

The gastrointestinal effects of GLP-1 agonists require careful consideration in the context of an already compromised digestive system, and UK product licences include specific cautions regarding use in severe gastrointestinal disease

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Its important to grasp this conversion clearly, as accurate dosing plays a crucial role in effective treatment and helps minimize potential side effects