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Both GLP-1 receptor agonists and metformin are commonly used to manage insulin resistance , but they work in different ways

Q5: Can GLP-1s be used for non-diabetic weight loss

Starting at a conservative dose and titrating slowly makes sense for anyone transitioning from a dual agonist to a triple agonist

Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, though these medications are often collectively referred to as incretin-based therapies

In clinical trials of Rybelsus (the previous formulation of the Ozempic pill), HbA1c levels reduced by 1.2%1.4% from an average of 8% after 26 weeks of treatment