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These hormonal shifts may occur through: Direct effects on hormone production Changes in body composition from weight loss Alterations in insulin sensitivity Potential Cause #2: Brain Reward System Effects Ozempic works by targeting areas of the brain that control both appetite and pleasure responses

& Andersen, J

M., Streinu, D

Large cardiovascular outcome trials have not shown increased arrhythmic events with GLP-1 receptor agonists in the general population

Furthermore, patients experiencing frequent hypoglycemia, poor glycemic control on current insulin regimens, or those using complex treatment strategiessuch as multiple daily injectionsmay benefit from a switch to a simplified regimen with combination basal insulin and GLP-1 agonists [36]

[1] [2] Clinical trials have demonstrated robust efficacy, with A1C reductions of 1.9% to 2.4% and weight loss of approximately 15% at 5 mg and 20-21% at 10-15 mg of baseline body weight in the SURMOUNT-1 trial