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"Chronic kidney disease is very serious and common in patients living with type 2 diabetes and represents a critical need for adults living with these comorbidities

In effect, the body composition ratio improved, shifting toward a leaner phenotype overall

The trial found a reduction in HFH, urgent HF visits, or cardiovascular death with dapagliflozin compared to placebo (16.4% versus 19.5%

The NDA was based on results from the OASIS-4 trial in adults with obesity or overweight

Preparation of Isolated GCs As previously reported [16], GCs were isolated by enzymatic digestion of retinal tissue with papain and mechanical separation