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That led them to examine whether GLP-1s might affect bone and other connective tissue more broadly

ArticlePubMedPMC 59

Mounjaro (tirzepatide) : The SURMOUNT trials demonstrated even greater efficacy, with average weight loss of 22.5% at the highest dose after 72 weeks

Bottom line: Oral GLP-1 supplements have a more substantiated evidence base than patches

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Furthermore, we did not use operationalized criteria (for example, Diagnostic and Statistical Manual 5th edition) to define the populations of interest because these would not be applicable across animal and human studies, but instead relied on the definitions provided by the individual articles