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Patients treated with sitagliptin exhibited a significant mean decrease from baseline in body weight compared to a significant weight gain in patients administered glipizide (-1.5 kg vs +1.1 kg)

Month 612 Significant Transformation Continued fat loss with improved appetite regulation

These agents include semaglutide (Ozempic for diabetes, Wegovy for obesity), liraglutide (Victoza for diabetes, Saxenda for obesity), dulaglutide (Trulicity, diabetes only), and tirzepatide (Mounjaro for diabetes, Zepbound for obesity)with tirzepatide being a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist

Importantly, however, neither are a magic jab that work in isolation

Six years later, the diabetes drug received additional approval as a treatment to reduce the risk of harmful cardiovascular events like strokes and heart attacks in adults with Type 2 diabetes who have cardiovascular risks or disease

GLP-1 medications work in part by slowing down stomach emptying, leading to increased feelings of fullness