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The most commonly reported adverse effects were gastrointestinal in nature , including: Nausea Vomiting Diarrhoea Constipation Decreased appetite These effects were generally mild to moderate in severity, most prevalent during dose escalation, and tended to diminish over time

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Phase I and II cannabinoid disposition in blood and plasma of occasional and frequent smokers following controlled smoked cannabis

10.1016/S0140-6736(09)62124-3

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These medications help signal fullness to the brain, which may reduce hunger and support portion control