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Description
The phase III SURMOUNT-3 trial by Thomas et al207 evaluated tirzepatide use following intensive lifestyle interventions

silymarin in 5-week-old male Wistar rats, starting at the third week of NAFLD induction and continued for another 3 weeks

One of the major reasons is the high dropout rate, 11 possibly due to the nausea-related side effects and importantly the fact that these formulations are till date injectable

however, shared decision-making between the primary care physician and patient is important for improving patient outcomes

The best factors to look at are effectiveness, frequency of dosing and side effect profiles

S.ChenZ
