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Description
The medications work by affecting blood sugar and can cause low blood sugar in some patients, particularly when combined with other drugs for type 2 diabetes
A few shed a significant amount, and others experience less
At 1.0 mg (used in STEP 2 as the lower comparison arm), average weight loss was 7.0%
Key methodological challenges limiting causal inference include confounding by indication, whereby depression itself is a robust risk factor for dementia (hazard ratio approximately 2.0) and residual confounding persists despite the use of propensity score methods
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CrossRef Kosiborod MN, Bhatta M, Davies M, et al
