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Description
Introduction and Background GLP-1 (Glucagon-Like Peptide-1) is a hormone that has gone from a physiological curiosity to a therapeutic powerhouse in recent decades

GLP-1, the endogenous agonist of GLP-1R, is predominantly synthesized in enteroendocrine cells of the distal small intestine and secreted in the blood when food enters the duodenum [4, 5]

Additionally, the medication hasn't been studied in children under 18 years of age
For most patients asking about an oral GLP-1 pill for weight loss in 2026, the conversation is really about Foundayo and oral Wegovy

In addition, both have extra-pancreatic functions that impact appetite regulation in the CNS

These expanded uses position GLP-1s as multi-system therapies, not just treatments for diabetes or high obesity rates
