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JAMA Intern Med 2016;176:1464-73.ArticlePubMed 30

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Participants receiving the highest dose of 12 mg lost an average of 24.2% of their body weight, compared to just 2.1% with placebo

feelings of frustration, guilt and helplessness about managing diabetes), interpersonal issues (feelings of isolation or lack of understanding from others about the challenges of living with diabetes) and poor access to good quality care [222]

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