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New study points to a possible link Switching APOE4 to APOE2 in adult mice reduces Alzheimers pathology and improves memory Current research suggest that this enzyme is overactive during manic episodes, hence it relevant in the management of the condition

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An article on this combination for treating T2 diabetes and a separate article on treating those obese without DM just appeared in NEJM

Changes in body weight in relation to mortality in 6441 European middle-aged men: the Seven Countries Study

Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine
