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Additional best practices include: never reusing needles, as this increases infection risk and causes needle dulling that makes injections more painful

Berberine also modulates gut microbiota composition, increasing populations of bacteria that produce short-chain fatty acids like butyrate, which in turn stimulate GLP-1 release

Role of GABA release from leptin receptor-expressing neurons in body weight regulation

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Average BMI ranged from the mid-30s to the high 30s