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At study entry, 38% of the patients were taking sodium glucose cotransporter 2 (SGLT2) inhibitors or glucagon-like peptide-1 receptor agonists (GLP-1 RAs), medications for diabetes that have been shown to have beneficial effects on heart disease, including reducing heart failure, heart attacks and strokes

Regulators (like the FDA in the U.S.) might be pushed to update labeling, add warnings, or require additional studies to better understand long-term effects

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