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Dehydration Risk Increases GLP-1 users often: eat less drink less feel less thirsty Alcohol: increases fluid loss increases electrolyte imbalance This can lead to: headaches fatigue constipation (already common on GLP-1s) dizziness Hydration becomes much more important

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes and Obesity (TRIUMPH-2)

So you may have hair loss or depression while using the drug

It attacks the core drivers of type 2 diabetes: hepatic and peripheral insulin resistance, ectopic lipid accumulation, and compensatory hyperinsulinemia

That's why PlexusDx recommends addressing reflux early with dietary changes, medication, or dose adjustments rather than ignoring it

While genetic markers do not predict exact side effects, they may help provide context for why GI sensitivity varies across individuals and support a more personalized conversation with your healthcare provider