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Appetite Rebound: The Primary Physical Change Between days four and seven of stopping semaglutide, most patients report a noticeable increase in hunger and food cravings

Additionally, if you develop symptoms suggestive of gallbladder diseasesuch as right upper abdominal pain, particularly after eating fatty foods, accompanied by nausea or jaundicecontact your GP, as rapid weight loss can increase the risk of gallstones, a warning highlighted in the MHRA safety information for GLP-1 receptor agonists