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reported a three-fold higher risk of major depression, and a doubled risk for anxiety and suicidal behavior in a large ( n = 11,683,623) retrospective study of GLP-1RA users utilizing the TrinetX database (100)

This emerging intersection of metabolic and mental health requires a nuanced approach that few providers are equipped to address How GLP-1 Medications Affect Your Brain and Mental Health Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone in your gut that regulates blood sugar
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