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It can increase heart rate, so individuals with pre-existing heart conditions should be closely monitored when utilising this peptide in clinical research

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Weight-loss trials can measure body weight, metabolic markers, adverse events, and defined clinical endpoints

The rate of gastrointestinal events was increased with semaglutide and there was an unexpected increase in retinopathy complications with semaglutide (vitreous haemorrhage, blindness or conditions requiring treatment with an intravitreal agent or photocoagulation)