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Learn More Metformin A medication indicated for the treatment of Type 2 Diabetes, which may also be prescribed for weight loss if deemed appropriate by a healthcare provider

While these drugs can aid weight loss, theyre not a silver-bullet, as evidence suggests most people regain weight after treatment, commented Jo Harby, Director of Health Information at Cancer Research UK

10.1038/s41386-018-0010-3 25 HernandezN

The advent and efficacy of injectable, and now oral, glucagon-like peptide-1 receptor agonists (GLP-1RAs) such as semaglutide (Ozempic/Wegovy, Novo Nordisk) or tirzepatide (Mounjaro/Zepbound, Eli Lilly and Company) has changed the weight loss landscape forever

These medications are now FDA-approved for patients who have higher body weight with other conditions like heart attack, stroke, peripheral arterial disease or sleep apnea

Baretic et al