glp 1 alzheimer's GLP-1 improves the neuronal supportive ability of astrocytes in disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway GLP-1 Microdosing, Brain Health &
Description
L., Berkowitz, K., Shreiner, B

95% CI 0.66, 0.75)

Tirzepatide is FDA-approved (for diabetes and weight loss, depending on the brand) and works as a dual-agonist, targeting GLP-1 and GIP receptors to reduce appetite, improve insulin response, and support weight loss

In November 2025, the Trump administration announced landmark agreements with Eli Lilly and Novo Nordisk reducing the monthly price of GLP-1 weight-loss drugs from over $1,000 to as low as $245 for eligible patients

Active medication supply was constructed using dispense dates and days supply

Excitation light was delivered at 435/9 nm (455 nm cut-off), and emitted light was detected at 485/15 nm (CFP) or 535/15 nm (YFP) 31,34,35,36