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Clinical evidence The effectiveness of combination therapy with PIO (1530 mg daily) and tofogliflozin (TOFO 20 mg daily) for 24 weeks was investigated in 32 patients who experienced T2D and NAFLD in an open-label RCT [116]

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Current guidelines recommend surgery if you have: BMI 40 kg/m BMI 35 kg/m with obesity-related health conditions Surgical procedures include: Roux-en-Y gastric bypass Sleeve gastrectomy Adjustable gastric banding Bilio-pancreatic diversion with duodenal switch Endoscopic sleeve gastroplasty (ESG) offers a newer, minimally invasive option