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Los alimentos permanecen en el estmago por ms tiempo, lo que enva seales de plenitud al cerebro

Patients should contact their GP or prescribing clinician if they experience: Severe or persistent abdominal pain , particularly in the upper right quadrant or radiating to the back, which could indicate biliary complications such as bile duct stones or pancreatitis Persistent vomiting that prevents adequate fluid or medication intake, risking dehydration Signs of dehydration including dark urine, dizziness, reduced urination, or extreme thirst Jaundice (yellowing of skin or eyes), which may suggest bile duct obstruction Severe diarrhoea lasting more than 48 hours or accompanied by blood Unexplained fever with abdominal symptoms Pancreatitis is a rare but serious potential side effect of GLP-1 receptor agonists

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Patient education and regular monitoring are crucial, especially for those reporting persistent abdominal symptoms while taking a GLP-1RA for the control of diabetes or weight loss

TLR4 is highly expressed in microglia, and its signaling pathway is linked to activated microglial phenotypes, which are responsible for the adverse effects of obesity on the hippocampus and other brain regions [47]

Some formulations stimulate metabolic pathways that increase the bodys energy expenditure even at rest
