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eTable 2 in Supplement 2)

Under normal conditions, GLP-1 helps your body: release insulin when blood sugar rises reduce glucagon when appropriate slow how quickly food leaves the stomach send fullness signals to the brain reduce appetite after a meal GLP-1 medications imitate or amplify this natural pathway, but they last much longer in the body than your natural GLP-1 hormone

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Tirzepatide storage temperature quick reference This chart summarizes the key temperature thresholds for every type of tirzepatide formulation

[1] [4] However, refrigerated storage is preferred when possible