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Participants were randomly assigned 1:1 to once-weekly 1 mg semaglutide or placebo

Some patients find that liquid protein sources (shakes, smoothies) are better tolerated than solid foods when nausea or early satiety is prominent

This review also highlights the existing queries and evidence gaps in DPP-4 inhibitor research

Ratner RE, Maggs D, Nielsen LL, et al

Medications That Reduce GLP-1 Efficacy Through Gastric Mechanisms Anticholinergic drugsincluding certain antihistamines, antispasmodics, and some antidepressantsslow gastric motility, potentially reducing GLP-1 absorption and effectiveness