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While metformin remains the first-line treatment for T2D, GLP-1s may be used in combination with metformin for additional benefits

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Results The leg fat to total fat (LF/TF) ratio showed a negative relationship with many factors, including body mass index, waist circumference, blood pressure, fasting blood glucose, and liver enzyme levels

Its a structured dose escalation ranging from 2.5 mg to 15 mg

The logic is that full therapeutic doses cause appetite suppression so dramatic that maintaining the caloric intake needed for training becomes nearly impossible

Week one is the most uncertain