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Pharmacokinetic study Plasma agonist concentration after a single IP injection (24 nmol kg 1 ) was measured with an exendin-4 C-terminus-specific ELISA (Phoenix Pharmaceuticals), a peptide region that does not differ between agonists, hence equally detecting exendin-4 and exendin-phe1 (confirmed by analysis of known concentrations of each agonist)
Its underexploitation in metabolic indications likely reflects disciplinary silos rather than a lack of biological relevance
Cushing's disease and idiopathic intracranial hypertension: case report and review of underlying pathophysiological mechanisms
