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The Gut-Brain Axis and Emotional Eating GLP-1 impacts the gut-brain axis an intricate communication system between the gut microbiota and brain via neural, immune and hormonal signalling (Singh et al, 2024)

Additionally, a case report highlighted that liraglutide therapy, in contrast to insulin, reduced C-peptide (CPR) concentrations and improved glucose control, along with enhanced quality of life for a patient with T2DM and active CD [228]

The 2026 Standards of Care by the American Diabetes Association (ADA) recommend them for adults with type 2 diabetes who also have obesity or overweight, atherosclerotic cardiovascular disease, heart failure, chronic kidney disease or metabolic-associated steatotic liver disease [4]

[DOI] [PubMed] [Google Scholar] 58

Clinical trials show patients using semaglutide achieve 15-22% body weight reduction over 68 weeks, making these compounds among the most effective pharmacological weight loss tools available today