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PMID 17308849
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For an imperfect comparison, the discontinuation rate seen in the landmark STEP trials for semaglutide was around 7%
This can increase the risk of the drainage angle closing in some people, leading to acute angle-closure glaucoma
Discussing these alternatives with your doctor ensures you choose the best path forward for relief and health
Furthermore, in PCO patients with relatively low estrogen, metformin can treat hyperandrogenism, improve plasma estrogen levels, normalize menstrual irregularities, increase progesterone receptor expression, and improve progesterone concentration [109,110,111,112,113]
