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diet drug semaglutide Use of new drugs likely to mushroom— Harvard Gazette GLP-1 weight-loss drug popularity reaches

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Group one (N=40) was given long-acting basal plus 1.0 mg SC semaglutide

diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

Clinical evidence The SURMOUNT-1 trial found that participants without diabetes lost an average of 22.5% of body weight at the 15 mg dose after 72 weeks

diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

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diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

Not all patients are candidates for oral therapy

diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

Diabetes 58 , 16041615, (2009)

diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

NEJM 2017;377:2063-72 NAFLD: progression of disease Liver histology in NAFLD Histology scoring NAS (NAFLD Activity Score), reflects disease activity: unweighted composite of Steatosis (0 to 3) Lobular inflammation (0 to 3) Ballooning (0 to 2) SAF Score: semi-quantitative score of Steatosis (0 to 3) Activity (lobular inflammation + ballooning) = NAS (0 to 8) Fibrosis (0 to 4) Adapted from Chalasani N

diet drug semaglutide Use of new drugs likely to mushroom Harvard Gazette GLP-1 weight-loss drug popularity reaches

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