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Description
The portfolio holds 28 companies that are involved with GLP-1 drugs as well as the broader supply chain supporting this segment
It has been shown that the administration of the GLP-1 receptor agonist exendin-4 results in the expansion of pancreatic duct glands in rats, and acceleration of the formation of dysplastic lesions and chronic pancreatitis in the KrasG12D mouse model [63]
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A meta-analysis of available cardiovascular outcome trial data argues against any effect of GLP-1RA on pancreatitis and pancreatic cancer incidence
When those conditions change, the molecule can unfold, aggregate, or degrade into fragments that no longer activate your GLP-1 receptors
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