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[DOI] [PubMed] [Google Scholar] 64.Shibue K, Yamane S, Harada N, Hamasaki A, Suzuki K, et al

Step three: combination and intensification For patients who do not reach their targets on either medication alone, combining basal insulin with a GLP-1 agonist is an increasingly popular strategy

A large retrospective study in JAMA Neurology (2025) identified more than 44,000 IIH patients and then compared matched cohorts

doi: 10.1038/s42255-023-00966-w 75 NrregaardPKDeryabinaMATofteng SheltonPFogJUDaugaardJRErikssonPOet al

For a deeper comparison of the first two, see our semaglutide vs tirzepatide comparison

doi: 10.1177/0145721710376328
