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Its difficult to distinguish direct anti-inflammatory effects from the benefits of weight loss and improved metabolic health, but the pattern is consistent enough to warrant further study. A 2025 study found that RA patients with a BMI over 27 taking GLP-1 medications showed improvements in symptoms and disease activity

The simulations suggested that moving from weekly to every 14 days preserved about 70% of weight loss seen with weekly dosing, and even monthly dosing maintained roughly half of the effect

Cell Metabolism, 35(2), 253273

Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists

Step 2: Participate in a telehealth consultation

Researchers havent found a direct link to the medication, but if you notice any concerning mental health changes in your child, reach out to your provider right away