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All references FDA: Concerns with unapproved GLP-1 drugs used for weight loss NEJM (2023): Retatrutide Phase 2 trial in obesity Eli Lilly: Phase 2 retatrutide results published in NEJM Eli Lilly (Dec 2025): Phase 3 TRIUMPH-4 topline results announcement ClinicalTrials.gov: NCT05882045 (TRIUMPH-3) Drugs.com: Retatrutide status & timeline Lilly Trials: TRIUMPH-3 summary page

Furthermore, the review article explores tirzepatide's effects on cardiovascular and kidney function, highlighting potential renal benefits for diabetic and elevated cardiovascular risk individuals

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We want people to be active, but no heavy-duty exercise in the beginning, advises Dr

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Petersen N, Frimurer TM, Terndrup Pedersen M, Egerod KL, Wewer Albrechtsen NJ, Holst JJ, et al