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these drugs include glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors [13, 14]

Clujul Med

Drug Targets 11 (2), 9298 (2011)

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[DOI] [PubMed] [Google Scholar] 108.Exendin-4, an analogue of glucagon-like peptide-1, attenuates hyperalgesia through serotonergic pathways in rats with neonatal colonic sensitivity

Thus, we speculate that daily oral semaglutide may not induce the same degree of tachyphylaxis as the weekly subcutaneous semaglutide