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Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: The STEP 3 randomized clinical trial

Zepbound is a Food and Drug Administration (FDA)-approved medication on November 2023 for chronic weight management in adults who are obese or are overweight with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

GLP-1R is represented as cartoon (cyan) with the ECD coloured brown

Gonlachanvit S, Hsu CW, Boden GH, et al

Their primary job is to help the body manage the influx of nutrients, particularly glucose

One year after stopping semaglutide 2.4 mg, participants regained two-thirds of their prior weight loss