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N Engl J Med (2011) 364:82941

NICE guidance supports their use in type 2 diabetes for people with established cardiovascular disease or high cardiovascular risk, or when additional therapy is needed despite metformin and/or SGLT2 inhibitors

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For example, tracking your waist circumference with a tape measure once a month can reveal fat loss even if your weight is holding steady

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Insulin lispro is a rapid-acting insulin, while insulin lispro protamine is an intermediate-acting insulin