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2019;30(5):987-996.e986

Obesity, particularly in those with android body fat distribution, are at increased risk of NAFLD and disease progression and individuals with complications such as hypertension, knee osteoarthritis, or sleep apnea should also be screened for advanced liver disease

Clinical trials of semaglutide show that appetite suppression occurs independently of meal timing, but early meal timing (injection before eating) reduces nausea in first-time users

In individuals with compromised liver function or those taking multiple hepatotoxic compounds, concurrent use warrants baseline and periodic liver function tests (AST, ALT, bilirubin)

[Google Scholar] 205.Temes CM, Boccagno C, Gold AK, Kobaissi H, Hsu I, Montinola S, et al

Factor V Leiden has been linked in many studies to an increased risk of deep vein thrombosis and pulmonary embolism
