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These pathways operate through several mechanisms: The primary signaling cascade involves dual pathways: (1) Gs-mediated activation of adenylyl cyclase leading to increased cAMP production and subsequent activation of protein kinase A (PKA) and exchange protein activated by cAMP (Epac), and (2) PI3K/Akt pathway activation [4]
Tashiro M, Ernst SA, Edwards J et al
GLP-1 Receptor Agonist Market Other Major and Innovative Companies 38
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Shankar SS, Shankar RR, Mixson LA, et al
Endocrinology 140:49044907
