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Evidence based on recent studies Initially, cases of intestinal obstruction associated with GLP-1 RAs were reported by the European Medicines Agency (EMA) in 2013 [9], and this safety signal is currently being monitored by the United States (US) FDA

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Correlation and mediation analysis We reported the correlation between the change in eGFR and change in body weight, systolic blood pressure and HbA 1c

[DOI] [PubMed] [Google Scholar] 44.Gao H., Geng T., Huang T., Zhao Q

GLP-1RAs contribute to improved glycemic control by lowering glycated hemoglobin (HbA1c) and promoting weight loss without causing hypoglycemia, a notable advantage over sulfonylureas and meglitinides