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Individuals with severe insulin resistance may require higher doses to achieve comparable metabolic improvements compared to those with milder metabolic dysfunction

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Semaglutide is most effective when combined with increased physical activity and a reduced-calorie diet, as recommended by the FDA

It is unknown whether semaglutide or tirzepatide causes medullary thyroid carcinoma in humans

If you take any of these and your weight loss has stalled, discuss alternatives with your prescribing provider

With tirzepatide, this fight appears to be less intense