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Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis

It is not strictly unexplored, nor is it a failed target

Immune regulation versus immune suppression A critical distinction that often gets lost in discussions about GLP-1 medications and autoimmunity

Recent Developments in Obesity Treatment Domain In February 2025, Eli Lilly launched 7.5 mg and 10 mg Zepbound (tirzepatide) vials for $499 through the Zepbound Self Pay Journey Program, alongside price reductions for 2.5 mg and 5 mg vials

Nutritional guidelines from The Obesity Society recommend these dietary changes to help maintain weight loss and prevent malnutrition and muscle loss , which can happen when you take diabetes weight loss drugs: Carbohydrates: 135245 grams a day from whole grains, fruits, vegetables, nuts and seeds, and dairy foods or dairy alternatives (soy milk) Fat: 2758 grams a day from fatty fish (tuna, salmon), seafood, avocado, nuts and seeds, and vegetable oils Fiber: 2125 grams daily for women and 3038 grams daily for men from vegetables, fruits, whole grains, beans and other legumes, and nuts and seeds Protein: 6075 grams daily from beans and other legumes, nuts and seeds, soy products, seafood, lean meat, poultry, low-fat dairy (milk, yogurt) or dairy alternatives, and eggs Exercise is the other key component that can help with weight loss and management with GLP-1 drugs (and weight loss in general, for that matter)

Once enrolled, adult patients in the EMPA-REG OUTCOME, EMPEROR-Reduced, EMPEROR-Preserved, and EMPA-KIDNEY trials were not required to discontinue therapy for worsening of eGFR to less than 20 mL/min/1.73 m2 or initiation of dialysis [see Clinical Studies (14.3, 14.4, 14.5)]