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Through the PI3K/AKT pathway, GLP-1RAs downregulate mitochondrial BCL2 interacting protein 3 expression, reduce doxorubicin-induced ROS production and -H2AX elevation, and ameliorate doxorubicin-induced cardiotoxicity (171)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Brown J.C., Pederson R.A., Jorpes E., Mutt V

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These patients are at a greater risk of major cardiovascular events such as stroke, heart attack, or death

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The mechanisms overlap but the magnitude is completely different

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The epiphany when dots are connected

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I get quick responses

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