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As the disease progresses, retinal ischaemia triggers the release of vascular endothelial growth factor (VEGF), stimulating the growth of fragile new blood vessels (neovascularisation) characteristic of proliferative diabetic retinopathy

Clinical experience shows that patients who push through mild nausea with consistent dosing adapt faster than those who skip doses or attempt dramatic diet changes

PMID 27059958

If you experience persistent pain, swelling, or signs of infection, skip that injection site for at least two weeks and rotate to a different location

( 10.1210/jc.85.11.4003) [DOI] [PubMed] [Google Scholar] 50.Hukshorn CJ, Westerterp-Plantenga MS & Saris WH

doi: 10.1016/j.ejmech.2013.09.059