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The regret rate among microdosers sits at approximately 22%, meaning roughly one in five researchers who try split dosing eventually return to weekly injections

International Journal of Neuropsychopharmacology , 27(1), pyad071

While semaglutide was associated with a significantly reduced risk of ADRD incidence in both patient groups, the association was stronger in younger adults than in older adults with largely non-overlapping confidence intervals (Supplemental Figures 13 and 14)

Compared to alternate T2D drugs, GLP-1RAs have a unique adverse effect profile that necessitates individualized prescribing based on tolerability and risk factors

In addition, if the eating window is longer, meals must often be eaten in an unfavorable setting (e.g., at work)

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