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Follow the Manufacturers Guidance The conservative approach recommended by Novo Nordisk (the maker of Ozempic and Wegovy) is to use a non-oral contraceptive or add a barrier method for four weeks after starting the medication and four weeks after each dose escalation

The understanding of how your body works and what it responds to

Your knownwell care team will review your health history to determine whether Zepbound is a safe option for you

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Macitentan (10 mg) Class: Endothelin Receptor Antagonist Used for: Pulmonary Arterial Hypertension (PAH) Metabolism: Mainly by CYP3A4 enzyme Major DrugDrug Interactions Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin) Decrease metabolism Increase Macitentan level _ Risk of liver toxicity, headache, edema Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, phenobarbital, St

Kini, R