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Patients may experience slower weight loss than anticipated or, in some cases, weight stability rather than reduction

The dual mechanism is why Eli Lilly positions tirzepatide as a distinct therapeutic option and why some patients specifically need it rather than a single-agonist alternative

Exenatide once weekly decreases urinary albumin excretion in patients with type 2 diabetes and elevated albuminuria: Pooled analysis of randomized active controlled clinical trials

Different effects of once-weekly and once-daily administered GLP-1RA semaglutide and liraglutide on bile acid diarrhea

In a variable course, the progression of the disease can lead, in addition to cirrhosis, to hepatocellular carcinoma

Hypoxia-inducible factor-1alpha is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy
