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This hormone performs several key functions: it stimulates insulin secretion, reduces glucagon secretion, and slows gastric emptying, all of which contribute to lower blood sugar levels

Mounjaro led to an average weight loss of 7.7 kg (17 lb) to 11.4 kg (25 lb)

These modifications include acylation of the peptide backbone with a spacer and a C-18 fatty di-acid chain to lysine at position 26, which mediates strong binding to albumin and potentially results in reduced renal clearance, and an amino-acid substitution in position 8, which results in reduced susceptibility to dipeptidyl peptidase-4 (DPP-4) degradation

N Engl J Med 384 , 9891002 (2021)

PlexusDx's Precision Peptide Genetic Test examines GLP1R and GIPR variants along with FTO and MC4R pathways to identify your genetic predispositions across 14 metabolic pathways and 150+ insights
