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This interval allows: GI side effects (nausea, vomiting, diarrhea) from the current dose level to subside The body to adapt to the rate of gastric emptying at that dose Clinicians to assess tolerability before increasing further Time to reach maximum dose At the four-week escalation schedule used in Phase 2 trials, participants reached the 12mg maximum dose at week 20 (after five four-week steps: 1mg, 2mg, 4mg, 8mg, 12mg)

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Communicating with Your Surgical and Medical Teams Your surgeon, anesthesiologist, and the team prescribing your GLP-1 medication must all be aware you are taking weight-loss therapy

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Myostatin-driven muscle hypertrophy: a double-edged sword in muscle physiology