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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) show substantial efficacy in regulating blood glucose levels and lipid metabolism, initially as an effective treatment for diabetes mellitus

Secondary endpoints included changes in body weight from baseline to end of study

Retatrutide has cleared a large hurdle in TRANSCEND-T2D-1, the first phase III trial testing the triple hormone receptor agonist in patients with type 2 diabetes, according to new top-line results released today by Lilly